Benjamin B
Department of Child Health, King Saud University, Abha, Saudi Arabia.
Ann Trop Paediatr. 1995 Sep;15(3):189-92. doi: 10.1080/02724936.1995.11747770.
Two children who presented with fever, thrombocytopenic purpura and mucosal haemorrhages proved to have brucellosis. Large platelets in the peripheral smear and megakaryocytic hyperplasia in the bone marrow suggested increased peripheral destruction as the primary mechanism of the thrombocytopenia. There was a prompt clinical and haematological response to specific anti-brucella chemotherapy. The nature of this association and its implications for brucella-endemic areas are discussed.
两名出现发热、血小板减少性紫癜和黏膜出血症状的儿童被证实患有布鲁氏菌病。外周血涂片可见大血小板，骨髓中巨核细胞增生，提示外周破坏增加是血小板减少的主要机制。针对布鲁氏菌的特异性化疗使患者在临床和血液学方面迅速好转。本文讨论了这种关联的性质及其对布鲁氏菌病流行地区的影响。
