在缺氧和好氧条件下将2,4-二氨基-6-硝基甲苯生物转化为一种新型代谢物。
Bioconversion of 2,4-diamino-6-nitrotoluene to a novel metabolite under anoxic and aerobic conditions.
作者信息
Gilcrease P C, Murphy V G
机构信息
Department of Chemical and Bioresource Engineering, Colorado State University, Fort Collins 80523, USA.
出版信息
Appl Environ Microbiol. 1995 Dec;61(12):4209-14. doi: 10.1128/aem.61.12.4209-4214.1995.
Abstract
Under nitrate-reducing, nongrowth conditions, a Pseudomonas fluorescens species reduced 2,4,6-trinitrotoluene to aminodinitrotoluenes, which were then further reduced to diaminonitrotoluenes. 2,4-Diamino-6-nitrotoluene (2,4-DANT) was further transformed to a novel metabolite, 4-N-acetylamino-2-amino-6-nitrotoluene (4-N-AcANT), while 2,6-diamino-4-nitrotoluene (2,6-DANT) was persistent. Efforts to further degrade 2,4-DANT and 2,6-DANT under aerobic, nitrogen-limited conditions were unsuccessful; 2,6-DANT remained persistent, and 2,4-DANT was again transformed to the 4-N-AcANT compound.
摘要
在硝酸盐还原、非生长条件下，一种荧光假单胞菌将2,4,6-三硝基甲苯还原为氨基二硝基甲苯，然后进一步还原为二氨基硝基甲苯。2,4-二氨基-6-硝基甲苯（2,4-DANT）进一步转化为一种新型代谢物4-N-乙酰氨基-2-氨基-6-硝基甲苯（4-N-AcANT），而2,6-二氨基-4-硝基甲苯（2,6-DANT）则具有持久性。在有氧、氮限制条件下进一步降解2,4-DANT和2,6-DANT的尝试未成功；2,6-DANT仍具有持久性，2,4-DANT再次转化为4-N-AcANT化合物。
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