Korematsu S
Department of Pediatrics, Oita Medical University.
Arerugi. 1995 Sep;44(9):1140-9.
Changes in ECG R-R intervals and blood pressure (lye and stand) were assessed by the autoregressive power spectral analysis method in 40 asthmatic children (age range: 2-16 years, mean +/- SD: 9.4 +/- 4.1 years). Significantly lower low frequency (LF: < or = 0.1 cycle/beat) power and high frequency (HF: 0.1-0.5 cycle/beat) power of R-R intervals were detected in severe type. LF fluctuations in R-R intervals are known to be mediated by the parasympathetic nervous system and the beta-adrenergic nervous system, while HF fluctuations in R-R intervals are mediated by the parasympathetic nervous system, LF fluctuations in systolic blood pressure by the alpha-adrenergic nervous system. The results suggested parasympathetic nervous system disorder especially in severe asthmatic children. Thus, spectral analysis of variability in R-R intervals and blood pressure are a useful tool for quantifying autonomic nervous system activity.
采用自回归功率谱分析方法，对40例哮喘儿童（年龄范围：2 - 16岁，平均±标准差：9.4±4.1岁）的心电图R - R间期和血压（卧位和立位）变化进行了评估。在重度哮喘类型中，检测到R - R间期的低频（LF：≤0.1次/搏周期）功率和高频（HF：0.1 - 0.5次/搏周期）功率显著降低。已知R - R间期的LF波动由副交感神经系统和β - 肾上腺素能神经系统介导，而R - R间期的HF波动由副交感神经系统介导，收缩压的LF波动由α - 肾上腺素能神经系统介导。结果提示尤其是重度哮喘儿童存在副交感神经系统紊乱。因此，R - R间期和血压变异性的频谱分析是量化自主神经系统活动的有用工具。
