云南繁缕中的环肽

Cyclopeptides from Stellaria yunnanensis.

作者信息

Zhao Y R, Zhou J, Wang X K, Huang X L, Wu H M, Zou C

机构信息

Department of Medicinal Chemistry of Natural Products, School of Pharmacy, West China University of Medical Sciences, Chengdu, People's Republic of China.

出版信息

Phytochemistry. 1995 Nov;40(5):1453-6. doi: 10.1016/0031-9422(95)00351-7.

DOI:10.1016/0031-9422(95)00351-7

PMID:8534403

Abstract

In a previous paper, we reported the structural elucidation of stellarin A, a new cyclic heptapeptide, from the fresh roots of Stellarina yunnanensis Franch. Further chemical study on this plant led to the isolation of another two new cyclopeptides named stellarin B and C. Their structures were established to be cyclo(Gly-Ser-HOIle-Phe-Phe-Ala) and cyclo(Gly-Ser-HOIle-Phe-Phe-Ser), respectively, by spectral methods.

摘要

在之前的一篇论文中，我们报道了从云南海石竹新鲜根中分离出的一种新的环七肽——海石竹素A的结构解析。对该植物的进一步化学研究导致分离出另外两种新的环肽，命名为海石竹素B和C。通过光谱方法确定它们的结构分别为环（甘氨酸-丝氨酸-异亮氨酸-苯丙氨酸-苯丙氨酸-丙氨酸）和环（甘氨酸-丝氨酸-异亮氨酸-苯丙氨酸-苯丙氨酸-丝氨酸）。