Nitrini R, Mathias S C, Caramelli P, Carrilho P E, Lefèvre B H, Porto C S, Magila M C, Buchpiguel C, de Barros N G, Gualandro S
Department of Neurology, Faculty of Medicine, University of São Paulo, Brazil.
Alzheimer Dis Assoc Disord. 1995 Fall;9(3):146-51.
One hundred consecutive outpatients with dementia were prospectively studied to investigate the diagnoses of dementing diseases and to correlate these diagnoses with socioeconomic status and with education. Alzheimer disease was the most common cause of dementia (54%), followed by vascular dementia (20%). Eight patients presented with potentially reversible causes of dementia. These frequencies are similar to those reported by case register studies from Western Europe and the United States. We did not find differences in the frequencies of the dementing diseases according to socioeconomic status or education. Alzheimer disease was the most common cause of dementia in all socioeconomic classes. Potentially reversible dementias, vascular dementias, and other secondary dementias were not more frequent in the lower socioeconomic strata. There was a trend to a higher frequency of vascular dementia among patients with less education, but this was not statistically significant.
对100例连续性门诊痴呆患者进行前瞻性研究，以调查痴呆性疾病的诊断，并将这些诊断结果与社会经济地位和教育程度相关联。阿尔茨海默病是痴呆最常见的病因（54%），其次是血管性痴呆（20%）。8例患者存在潜在可逆性痴呆病因。这些频率与西欧和美国病例登记研究报告的频率相似。我们未发现根据社会经济地位或教育程度划分的痴呆性疾病频率存在差异。在所有社会经济阶层中，阿尔茨海默病都是痴呆最常见的病因。潜在可逆性痴呆、血管性痴呆和其他继发性痴呆在社会经济地位较低阶层中并不更常见。受教育程度较低的患者中血管性痴呆频率有升高趋势，但无统计学意义。
