Montorsi F, Guazzoni G, Rigatti P, Pizzini G, Miani A
Institute of Human Anatomy, University of Milan School of Medicine, Italy.
J Endourol. 1995 Aug;9(4):333-7. doi: 10.1089/end.1995.9.333.
We critically reviewed our 6-year experience with transrectal microwave hyperthermia of the prostate for benign prostatic hyperplasia (BPH) in 320 patients either at high surgical risk or refusing surgery. Transrectal prostatic hyperthermia was given in five to ten 60-minute sessions with an intraprostatic temperature ranging from 42 degrees to 43.5 degrees C. Although an amelioration of symptoms and urodynamic measures was seen initially in most patients, only residual urine volume showed a statistically and clinically significant improvement at the long-term follow-up. According to maximum flow nomograms, bladder outlet obstruction was not resolved by the treatment. We conclude that although the transrectal hyperthermia proved to be a safe procedure, it did not cure BPH in the long term. Considering the results seen with newer nonsurgical procedures such as prostatic stents and prostatic lasers, we believe that transrectal hyperthermia should not be recommended to symptomatic BPH patients.
我们对320例因良性前列腺增生(BPH)而具有高手术风险或拒绝手术的患者进行经直肠微波热疗前列腺的6年经验进行了严格审查。经直肠前列腺热疗以5至10次60分钟的疗程进行,前列腺内温度范围为42摄氏度至43.5摄氏度。尽管大多数患者最初症状和尿动力学指标有所改善,但在长期随访中,仅残余尿量显示出统计学和临床上的显著改善。根据最大尿流率列线图,治疗并未解除膀胱出口梗阻。我们得出结论,尽管经直肠热疗被证明是一种安全的方法,但从长期来看它并不能治愈BPH。考虑到诸如前列腺支架和前列腺激光等更新的非手术方法所取得的结果,我们认为不应向有症状的BPH患者推荐经直肠热疗。