Izumikawa K, Iwasaki H, Ota M, Ikebe A, Hara K
Jpn J Antibiot. 1977 Feb;30(2):139-44.
Tetracycline is expected to be as effective as erythromycin in the treatment of pneumonia due to Mycoplasma pneumoniae. In this clinical trial 12 cases with pneumonia due to Mycoplasma pneumoniae were given doxycycline (Vibramycin "Pfizer'), a long-acting derivative of tetracycline. Judging from time periods required for defervescence, improvement in symptoms such as cough and disappearance of shadows on chest X-ray, the therapeutic effect of doxycycline was excellent in 8 cases and good in 4 cases.
预计四环素在治疗肺炎支原体引起的肺炎方面与红霉素效果相当。在这项临床试验中,12例肺炎支原体引起的肺炎患者接受了强力霉素(辉瑞公司的“威霸霉素”)治疗,强力霉素是四环素的长效衍生物。从退热所需时间、咳嗽等症状的改善以及胸部X光片阴影消失情况判断,强力霉素治疗效果极佳的有8例,良好的有4例。