视神经乳头分析仪和海德堡视网膜断层扫描仪：模拟白内障模型眼中地形测量的相对误差和可重复性。
Optic nerve head analyzer and Heidelberg retina tomograph: relative error and reproducibility of topographic measurements in a model eye with simulated cataract.
作者信息
Janknecht P, Funk J
机构信息
Jens Funk Universitäts-Augenklinik Killianstrasse 5, Freiburg, Germany.
出版信息
Graefes Arch Clin Exp Ophthalmol. 1995 Aug;233(8):523-9. doi: 10.1007/BF00183434.
BACKGROUND
We measured the relative error and reproducibility of the optic nerve head analyzer (ONHA) and the Heidelberg retina tomograph (HRT) in a model eye with a cataract that was simulated by Bangerter foils.
METHODS
There were two artificial discs and one retinal elevation (the latter could not be analyzed by the ONHA) that could be inserted into the model eye. The relative error of the parameter 'cup area' ('cup volume') of the ONHA for the measurement of artificial disc no. 1 changed from 1.1% (5.4%) without Bangerter foil to 7.9% (7.6%) with Bangerter foil 0.6. The standard deviation of the ONHA increased from 0.059 mm2 (0.1 mm3) without Bangerter foil to 0.142 mm2 (0.121 mm3) with Bangerter foil 0.6. With the smaller artificial disc no. 2, no measurements with Bangerter foils were obtained.
RESULTS
Relative error and reproducibility of the parameter 'volume below (above) surface' of the HRT did not show any consistent change with increasing intensity of the simulated cataract. With artificial disc no. 1, the relative error without Bangerter foil was 14.6%, while the worst relative error with one of the Bangerter foils 0.8 to 0.4 was 16.4%. The corresponding values for the standard deviation were 0.019 mm3 and 0.033 mm3. With the smaller artificial disc no. 2, the relative error without Bangerter foil was 6.3%, while the worst relative error with one of the Bangerter foils 0.8 to 0.2 was 18.3%. The corresponding values for the standard deviation were 0.016 mm3 and 0.017 mm3. The relative error in measuring a retinal elevation without a Bangerter foil was 2.3%, with a Bangerter foil 11.2-18.0%. The standard deviation was 0.068 mm3 without Bangerter foil and 0.013-0.023 mm3 with Bangerter foils.
CONCLUSION
Our data support the assumption that the HRT is able to measure fundus structures even in the case of opaque optical media. The HRT is superior to the ONHA in this regard.
背景
我们在一个用班格特滤光片模拟白内障的模型眼中，测量了视神经乳头分析仪（ONHA）和海德堡视网膜断层扫描仪（HRT）的相对误差和可重复性。
方法
有两个模拟视盘和一个视网膜隆起（后者不能由ONHA分析）可插入模型眼。对于1号模拟视盘测量，ONHA的“杯面积”（“杯容积”）参数的相对误差在没有班格特滤光片时为1.1%（5.4%），在使用0.6的班格特滤光片时变为7.9%（7.6%）。ONHA的标准差从没有班格特滤光片时的0.059平方毫米（0.1立方毫米）增加到使用0.6的班格特滤光片时的0.142平方毫米（0.121立方毫米）。对于较小的2号模拟视盘，未获得使用班格特滤光片的测量结果。
结果
HRT的“表面以下（以上）容积”参数的相对误差和可重复性并未随模拟白内障强度增加而呈现出一致变化。对于1号模拟视盘，没有班格特滤光片时相对误差为14.6%，而使用0.8至0.4的班格特滤光片中最差的相对误差为16.4%。标准差的相应值分别为0.019立方毫米和0.033立方毫米。对于较小的2号模拟视盘，没有班格特滤光片时相对误差为6.3%，而使用0.8至0.2的班格特滤光片中最差的相对误差为18.3%。标准差的相应值分别为0.016立方毫米和0.017立方毫米。没有班格特滤光片时测量视网膜隆起的相对误差为2.3%，使用班格特滤光片时为11.2% - 18.0%。没有班格特滤光片时标准差为0.068立方毫米，使用班格特滤光片时为0.013 - 0.023立方毫米。
结论
我们的数据支持以下假设，即即使在光学介质不透明的情况下，HRT也能够测量眼底结构。在这方面，HRT优于ONHA。
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