鼻泪管阻塞对药物性散瞳的影响。
The effect of nasolacrimal occlusion on drug-induced mydriasis.
作者信息
Loewenstein A, Sadeh A, Goldstein M, Lazar M
机构信息
Department of Ophthalmology, Ichilov Hospital, Tel-Aviv, Israel.
出版信息
Graefes Arch Clin Exp Ophthalmol. 1995 Aug;233(8):530-1. doi: 10.1007/BF00183435.
BACKGROUND
Nasolacrimal occlusion has been shown to improve the efficacy of some topically applied ocular drugs. The aim of this study was to investigate the effect of nasolacrimal occlusion on tropicamide-induced mydriasis.
METHODS
We compared pupillary dilatation by 0.125% tropicamide with and without nasolacrimal occlusion in 40 healthy volunteers.
RESULTS
Analysis of variance with repeated measures failed to show any advantage due to nasolacrimal occlusion in drug-induced mydriasis.
CONCLUSION
Nasolacrimal occlusion did not increase the mydriasis obtained with 0.125% tropicamide.
背景
鼻泪管阻塞已被证明可提高某些局部应用眼药的疗效。本研究的目的是探讨鼻泪管阻塞对托吡卡胺所致散瞳的影响。
方法
我们比较了40名健康志愿者在有或无鼻泪管阻塞情况下，0.125%托吡卡胺引起的瞳孔散大情况。
结果
重复测量方差分析未显示鼻泪管阻塞在药物性散瞳方面有任何优势。
结论
鼻泪管阻塞并未增加0.125%托吡卡胺所致的散瞳效果。
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