Huerta Bahena J, Padilla Arrieta P, Ayala Hernández J R
Departamento de Radioterapia, Hospital de Oncología, Centro Médico Nacional SXXI, IMSS Méx, D.F.
Ginecol Obstet Mex. 1995 Nov;63:443-7.
Between 1986 and 1992, 42 patients with carcinoma of the vulva diagnosis, were treated at the Hospital de Oncologia, CMN, SXXI. Mean age was 63 years. There was 1 case stage I, 5 stage II, 25 stage III, 4 stage IV, 2 with recurrent disease and 5 patients could not be classified. Local control was reached in 60% of patients however, 12 patients developed local recurrence after surgery and/or radiation therapy, finally 43% of patients remained disease free after a mean of 19 months of followup. In the subset of advanced disease patients treated with radical or preoperative radiation therapy (27 patients), 41% of them remained without disease. Mean radiation doses for patients treated only with radiation therapy was 6500 cGy. Late vulvar fibrosis and acute desquamative dermatitis, were the morbidity more frequently observed. New directions in the management of vulvar cancer must be developed to improve treatment results, in patients with advanced disease.
1986年至1992年间，42例经诊断为外阴癌的患者在墨西哥社会保险局第21综合医院肿瘤医院接受了治疗。平均年龄为63岁。其中I期1例，II期5例，III期25例，IV期4例，2例为复发性疾病，5例患者无法分类。60%的患者实现了局部控制，然而，12例患者在手术和/或放疗后出现局部复发，最终，平均随访19个月后，43%的患者无疾病生存。在接受根治性或术前放疗的晚期疾病患者亚组（27例患者）中，41%的患者无疾病生存。仅接受放疗的患者平均放疗剂量为6500 cGy。晚期外阴纤维化和急性脱屑性皮炎是最常观察到的并发症。必须探索外阴癌治疗的新方向，以改善晚期疾病患者的治疗效果。
