Arai T, Morita S, Nakano T, Gomi H, Fukuhisa K
Gan No Rinsho. 1986 Oct;32(12):1567-72.
Thirty-three patients suffering from squamous cell carcinoma of the vulva were treated with radiation therapy alone between 1961 and 1980 at the NIRS. The five-year survival rate and local control rate in each stage were 91% and 36% in T2 and 71% and 64% in T3, respectively. These results indicated that the early detection of recurrent tumor by close follow-up and an adequate retreatment procedure is very important for prolonging survival. Late recurrence, more than five years after treatment, appeared in 30% of the patients and this may be one of the special figures of postirradiated vulval carcinoma. The primary site was irradiated with external electron beams or radium needles, and better results were obtained with the later. Irradiation to the lymph node area in the pelvic cavity was necessary in patients with a more advanced stage of disease than T2.
1961年至1980年间，33例外阴鳞状细胞癌患者在日本国立放射医学综合研究所仅接受了放射治疗。各分期的五年生存率和局部控制率分别为：T2期91%和36%，T3期71%和64%。这些结果表明，通过密切随访早期发现复发性肿瘤以及采取适当的再治疗程序对于延长生存期非常重要。30%的患者出现了治疗后五年以上的晚期复发，这可能是放射治疗后外阴癌的一个特殊特征。原发部位采用外照射电子束或镭针照射，后者效果更佳。对于疾病分期超过T2期的患者，有必要对盆腔淋巴结区域进行照射。
