Kennedy G T, Barr J G, Goldsmith C
Department of Bacteriology, Royal Hospitals, Belfast.
J Clin Pathol. 1995 Oct;48(10):912-4. doi: 10.1136/jcp.48.10.912.
To analyse a continuously monitoring blood culture system with respect to the time to detection of various groups of organisms, their clinical importance, and the relative efficacy of the aerobic and anaerobic bottles.
Four thousand blood cultures were monitored and the information relating to the positive cultures was noted and analysed.
Four hundred and seventy seven blood cultures were detected as positive, 81% (387/477) of which were detected within 48 hours. The most pathogenic organisms were detected in the shortest period, less pathogenic later and those generally regarded as contaminants last. Clinically important isolates were also detected earlier. Many positive blood cultures were detected in only one bottle of the set, even those regarded as clinically important.
The management of continuously monitoring blood culture systems could be improved by considering time to detection trends. Clinicians should be aware of the relatively rapid detection of clinically important, positive blood cultures in relation to patient treatment.
分析一种连续监测血培养系统,观察其对各类微生物的检测时间、微生物的临床重要性以及需氧瓶和厌氧瓶的相对效能。
监测4000份血培养样本,并记录和分析与阳性培养结果相关的信息。
共检测到477份血培养阳性样本,其中81%(387/477)在48小时内被检测到。致病性最强的微生物在最短时间内被检测到,致病性较弱的微生物随后被检测到,而通常被视为污染物的微生物最后被检测到。具有临床重要性的分离株也较早被检测到。许多阳性血培养样本仅在一组中的一个瓶子中被检测到,即使是那些被视为具有临床重要性的样本。
通过考虑检测时间趋势,可改进连续监测血培养系统的管理。临床医生应意识到,就患者治疗而言,具有临床重要性的阳性血培养样本能相对快速地被检测到。