动态磁共振成像（MRI）和动态螺旋CT对富血管性肝细胞癌的检测
Detection of hypervascular hepatocellular carcinoma by dynamic MRI and dynamic spiral CT.
作者信息
Kim T, Murakami T, Oi H, Matsushita M, Kishimoto H, Igarashi H, Nakamura H, Okamura J
机构信息
Department of Radiology, Osaka University Medical School, Japan.
出版信息
J Comput Assist Tomogr. 1995 Nov-Dec;19(6):948-54. doi: 10.1097/00004728-199511000-00020.
OBJECTIVE
Our goal was to evaluate the detectability of hypervascular hepatocellular carcinomas (HCCs) by multislice dynamic MRI and dynamic spiral CT.
MATERIALS AND METHODS
Prior to transcatheter arterial chemoembolization (TACE) with iodized oil, the liver was subjected to T1- and T2-weighted SE-MRI, multislice dynamic MRI after intravenous bolus injection of Gd-DTPA, early phase imaging with spiral CT (dynamic spiral CT) after intravenous bolus injection of contrast medium (at a rate of 2 or 3 ml/s), and delayed phase CT in 64 patients with 208 HCC nodules. The detectability of HCCs by MRI and CT was evaluated retrospectively compared with CT after TACE as a gold standard.
RESULTS
The detectability of nodules < 1 cm in diameter was superior with dynamic MRI (67%) and dynamic spiral CT (50%) in comparison with SE-MRI (26%) and delayed phase CT (11%) (p < 0.01). The detectability of these tumors with dynamic MRI was significantly superior to that with dynamic spiral CT using an injection rate of 2 ml/s (p < 0.01), but not significantly different from that of dynamic spiral CT using a rate of 3 ml/s.
CONCLUSION
Dynamic MRI and dynamic spiral CT are comparable for detecting hypervascular intrahepatic metastases of HCC.
目的
我们的目标是通过多层动态磁共振成像（MRI）和动态螺旋CT评估高血供肝细胞癌（HCC）的可检测性。
材料与方法
在使用碘化油进行经动脉化疗栓塞（TACE）之前，对64例患有208个HCC结节的患者的肝脏进行T1加权和T2加权自旋回波MRI、静脉推注钆喷酸葡胺后的多层动态MRI、静脉推注造影剂（速率为2或3 ml/s）后的螺旋CT早期成像（动态螺旋CT）以及延迟期CT。将MRI和CT对HCC的可检测性与TACE后的CT进行回顾性比较，以TACE后的CT作为金标准。
结果
与自旋回波MRI（26%）和延迟期CT（11%）相比，动态MRI（67%）和动态螺旋CT（50%）对直径<1 cm结节的可检测性更高（p<0.01）。使用2 ml/s注射速率时，动态MRI对这些肿瘤的可检测性显著优于动态螺旋CT（p<0.01），但与使用3 ml/s速率的动态螺旋CT无显著差异。
结论
动态MRI和动态螺旋CT在检测HCC的高血供肝内转移方面具有可比性。
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