小肝细胞癌的检测：动态增强磁共振成像与多期多层螺旋CT扫描的比较
Detection of small hepatocellular carcinoma: comparison of dynamic enhancement magnetic resonance imaging and multiphase multirow-detector helical CT scanning.
作者信息
Zhao Hong, Yao Jin-Lin, Wang Ying, Zhou Kang-Rong
机构信息
Department of Radiology, Affiliated Fifth Hospital, Zhongshan University, Zhuhai 519000, Guangdong Province, China.
出版信息
World J Gastroenterol. 2007 Feb 28;13(8):1252-6. doi: 10.3748/wjg.v13.i8.1252.
Abstract
AIM
To compare the gadolinium-enhanced multiphase dynamic magnetic resonance imaging (MRI) and multiphase multirow-detector helical CT (MDCT) scanning for detection of small hepatocellular carcinoma (HCC).
METHODS
MDCT scanning and baseline MRI with SE T1-WI and T2-WI sequence combined with FMPSPGR sequence were performed in 37 patients with 43 small HCCs. Receiver operating characteristic (ROC) curves were plotted to analyze the results for modality.
RESULTS
The areas below ROC curve (Az) were calculated. There was no statistical difference in dynamic enhancement MDCT and MRI. The detection rate of small HCC was 97.5%-97.6% on multiphase MDCT scanning and 90.7%-94.7% on MRI, respectively. The sensitivity of detection for small HCC on MDCT scanning was higher than that on dynamic enhancement MRI. The sensitivity of detection for minute HCC (tumor diameter < or = 1 cm) was 90.0%-95.0% on MDCT scanning and 70.0%-85.0% on MRI, respectively.
CONCLUSION
MDCT scanning should be performed for early detection and effective treatment of small HCC in patients with chronic hepatitis and cirrhosis during follow-up.
摘要
目的
比较钆增强多期动态磁共振成像（MRI）和多期多层螺旋CT（MDCT）扫描检测小肝细胞癌（HCC）的效果。
方法
对37例患有43个小肝癌的患者进行MDCT扫描以及采用SE T1-WI和T2-WI序列联合FMPSPGR序列的基线MRI检查。绘制受试者操作特征（ROC）曲线以分析两种检查方式的结果。
结果
计算ROC曲线下面积（Az）。动态增强MDCT和MRI之间无统计学差异。小肝癌在多期MDCT扫描中的检出率分别为97.5% - 97.6%，在MRI中的检出率分别为90.7% - 94.7%。MDCT扫描对小肝癌的检测灵敏度高于动态增强MRI。微小肝癌（肿瘤直径≤1 cm）在MDCT扫描中的检测灵敏度分别为90.0% - 95.0%，在MRI中的检测灵敏度分别为70.0% - 85.0%。
结论
在随访过程中，对于慢性肝炎和肝硬化患者，应进行MDCT扫描以早期发现和有效治疗小肝癌。
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