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头孢唑肟和头孢曲松短期治疗对人外周血白细胞、血清免疫球蛋白及淋巴细胞亚群的影响。

Effect of short-term therapy with ceftizoxime and ceftriaxone on human peripheral WBC, serum immunoglobulins and lymphocyte subpopulations.

作者信息

Karakaya A, Gümüşay S, Yücesoy B, Hengirmen S

机构信息

Department of Toxicology, Faculty of Pharmacy, Ankara University, Turkey.

出版信息

Immunopharmacol Immunotoxicol. 1995 Nov;17(4):775-81. doi: 10.3109/08923979509037195.

DOI:10.3109/08923979509037195
PMID:8537612
Abstract

Serum immunoglobulins, peripheral white blood cells and lymphocyte subpopulation counts of twenty patients who received ceftizoxime and ceftriaxone for antimicrobial prophilaxis in surgery were examined in order to obtain a profile of the effects of these drugs on humoral and cellular immune system of human. No differences in the serum concentrations of IgG, IgM, IgA, peripheral blood lymphocytes and lymphocyte subpopulations 24 h and 48 h following the last dose of these two drugs were observed.

摘要

对20例在手术中接受头孢唑肟和头孢曲松进行抗菌预防的患者的血清免疫球蛋白、外周血白细胞和淋巴细胞亚群计数进行了检测，以了解这些药物对人体体液和细胞免疫系统的影响情况。在最后一剂这两种药物后的24小时和48小时，未观察到IgG、IgM、IgA的血清浓度、外周血淋巴细胞及淋巴细胞亚群有差异。

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