Ronna T, Lebwohl M
J Am Podiatr Med Assoc. 1995 Nov;85(11):717-8. doi: 10.7547/87507315-85-11-717.
Although more than 50% of warts resolve spontaneously within 2 years, many, if untreated, have the propensity to spread and cause considerable discomfort. There are several treatments to date; however, most cause some type of tissue damage. Because spontaneous resolution of warts can occur, the role of cimetidine in the treatment of warts remains controversial. Anecdotal reports suggest cimetidine may have a role in the treatment of plantar warts with no side effects or tissue damage. A double blind trial in a large population should be conducted to further verify the effects of treating viral warts with cimetidine.
尽管超过50%的疣会在2年内自行消退，但许多疣如果不治疗，有扩散的倾向并会引起相当大的不适。迄今为止有多种治疗方法；然而，大多数都会造成某种类型的组织损伤。由于疣可自行消退，西咪替丁在疣治疗中的作用仍存在争议。轶事报道表明西咪替丁可能在跖疣治疗中发挥作用且无副作用或组织损伤。应该在大量人群中进行双盲试验以进一步验证西咪替丁治疗病毒性疣的效果。
