Masamura K, Inaba R, Iwata H
Department of Hygiene, Gifu University School of Medicine, Japan.
Nihon Eiseigaku Zasshi. 1995 Oct;50(4):886-92. doi: 10.1265/jjh.50.886.
To evaluate the relationship between salivary components (calcium: Ca, total protein: T-Pro) and dental caries, we collected nonstimulated and expectorated saliva from 131 primary school children aged 11 years old. All salivary samples were taken in the morning (11:00-11:30 A.M.) on Feb. 17, 1994, while the subjects were at rest. The salivary Ca concentration (mg/dliter), total salivary protein concentration (mg/mliter) and salivary flow rate (mliter/min) were measured based on the salivary sample taken for each person for 30 minutes at most. For each subject the Ca secretion rate (micrograms/min), T-Pro secretion rate (micrograms/min) and Ca/T-Pro ratio were determined. The numbers of permanent teeth erupted, and decayed, missing and filled (DMF) teeth for each subject were obtained from dental records. For the entire group we observed that the numbers of DMF teeth were highly correlated with the numbers of permanent teeth erupted, hence for further analysis we restricted the subjects to 18 boys and 29 girls who were classified as dental age IIIC-IVA (according to Hellman's classification). Multiple linear regression analysis was employed using the number of DMF teeth as a dependent variable. When we included the variables for the Ca/T-Pro ratio, numbers of erupted permanent teeth, sex and salivary flow rate into the model as independent variables, there was a statistically significant association (P < 0.05) between the Ca/T-Pro ratio and the numbers of DMF teeth. However, in other models there was no significant association between the numbers of DMF teeth with Ca concentration, Ca flow rate, total protein concentration, or total protein flow rate.(ABSTRACT TRUNCATED AT 250 WORDS)
为评估唾液成分(钙:Ca,总蛋白:T-Pro)与龋齿之间的关系,我们收集了131名11岁小学生的非刺激性咳出唾液。所有唾液样本均于1994年2月17日上午(11:00 - 11:30)采集,当时受试者处于休息状态。根据为每人采集的唾液样本,最多测量30分钟的唾液钙浓度(mg/分升)、唾液总蛋白浓度(mg/毫升)和唾液流速(毫升/分钟)。为每个受试者确定钙分泌率(微克/分钟)、T-Pro分泌率(微克/分钟)和Ca/T-Pro比值。从牙科记录中获取每个受试者恒牙萌出数以及龋、失、补牙(DMF)数。对于整个群体,我们观察到DMF牙数与恒牙萌出数高度相关,因此为进一步分析,我们将受试者限制为18名男孩和29名女孩,他们被分类为牙龄IIIC - IVA(根据赫尔曼分类法)。以DMF牙数作为因变量进行多元线性回归分析。当我们将Ca/T-Pro比值、恒牙萌出数、性别和唾液流速等变量作为自变量纳入模型时,Ca/T-Pro比值与DMF牙数之间存在统计学显著关联(P < 0.05)。然而,在其他模型中,DMF牙数与钙浓度、钙流速、总蛋白浓度或总蛋白流速之间无显著关联。(摘要截断于250字)