Gifu Prefectural Health and Environment Research Center, Gifu.
Environ Health Prev Med. 1997 Oct;2(3):122-5. doi: 10.1007/BF02931977.
To investigate the relationship between dental caries and the salivary flow rate, secretory immunoglobulin A (sIgA) or other components in children, nonstimulated whole saliva was collected and teeth status was examined in 138 boys and 134 girls aged 11-12 years. The subjects were apparently healthy. The mean salivary flow rate was faster in boys than in girls (0.29 vs 0.18 ml/min, p < 0.001). In both sexes, secretion of salivary sIgA and three other components (total protein, calcium and amylase activity) was markedly dependent on salivary flow rates. These results suggest that basal components of resting saliva are secondarily secreted with the flow of saliva fluid. The mean erupted permanent teeth was 21.0 teeth (range: 10-28 teeth) in boys, and 23.0 teeth (13-28 teeth) in girls (sex-difference: p < 0.001). The means of DMFT, the DMFT ratio (% of DMFT to erupted permanent teeth) and DT+dt (sum of decayed permanent and milk teeth, an index for active caries) were 3.4 DMFT (range: 0-11 DMFT), 16.0% (0-40.0%) and 0.5 DT+dt (0-7 DT + dt) in boys, and 3.8 DMFT (0-12 DMFT), 16.2% (0-44.4%) and 0.8 DT+dt (0-5 DT+dt) in girls, respectively (sex-differences: p>0.05 in all). The salivary flow rate or the four salivary components (either concentration or secretion rate) used here had no relationship to the DMFT ratio or to DT+dt in either sex. Variation in the flow rate or in the basal components of resting saliva may not influence caries development in healthy children.
为了研究儿童龋齿与唾液流率、分泌型免疫球蛋白 A（sIgA）或其他成分之间的关系，我们收集了 138 名 11-12 岁男孩和 134 名女孩的非刺激性全唾液，并检查了他们的牙齿状况。这些受试者均无明显健康问题。男孩的唾液流率均值快于女孩（0.29 比 0.18ml/min，p<0.001）。在两性中，唾液 sIgA 及其他三种成分（总蛋白、钙和淀粉酶活性）的分泌均明显依赖于唾液流率。这些结果表明，基础唾液成分是随唾液的流动而继发分泌的。男孩的已萌出恒牙平均数为 21.0 颗（范围：10-28 颗），女孩为 23.0 颗（13-28 颗）（性别差异：p<0.001）。男孩的 DMFT 均值为 3.4DMFT（范围：0-11DMFT）、DMFT 比值（DMFT 占已萌出恒牙的百分比，0-40.0%）和 DT+dt（恒牙和乳牙龋齿之和，活跃性龋齿的一个指标，0-7DT+dt）分别为 16.0%和 0.5DT+dt，女孩的 DMFT 均值为 3.8DMFT（范围：0-12DMFT）、DMFT 比值（0-44.4%）和 DT+dt（0-5DT+dt）分别为 16.2%和 0.8DT+dt，两性间差异均无统计学意义（p>0.05）。无论在男性还是女性中，这里使用的唾液流率或四种唾液成分（浓度或分泌率）均与 DMFT 比值或 DT+dt 无关。健康儿童中，唾液流率或基础唾液成分的变化可能不会影响龋齿的发生。
