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[运用外斐氏凝集试验、补体结合试验和间接免疫荧光法测定地中海斑疹热的抗体动力学]

[Determination of antibody kinetics in Mediterranean spotted fever using the Weil-Felix agglutination test, complement fixation and indirect immunofluorescence].

作者信息

Punda-Polić V, Bradarić N, Milas I

机构信息

Odjel za mikrobiologiju, Medicinski fakultet Sveucilista u Zagrebu.

出版信息

Lijec Vjesn. 1995 Mar-Apr;117(3-4):73-6.

PMID:8538356
Abstract

The kinetics of antibodies in human cases of Mediterranean spotted fever was studied by applying Weil-Felix (WF) agglutination with Proteus OX antigens, complement fixation (CF) and indirect immunofluorescence (IF) tests with Rickettsia conorri antigen to 46 sera from 21 patients. The kinetics of specific (CF and IF) and nonspecific (WF) antibodies was similar. The percentage of the positive sera and geometric mean titers of antibodies reached the maximum after 14 days from the onset of illness.

摘要

通过对21例患者的46份血清应用普罗威登斯菌OX抗原进行外斐(WF)凝集试验、用康氏立克次体抗原进行补体结合(CF)试验和间接免疫荧光(IF)试验,研究了人类地中海斑疹热病例中抗体的动力学。特异性(CF和IF)抗体和非特异性(WF)抗体的动力学相似。从发病后14天起,阳性血清的百分比和抗体的几何平均滴度达到最大值。

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