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青光眼患者图形视网膜电图峰时延迟及其与运动感知对比度阈值的相关性

Delay of pattern electroretinogram peaks and its correlation to contrast threshold for motion perception in glaucoma.

作者信息

Komata M, Shirao Y, Watanabe M, Kawasaki K

机构信息

Department of Ophthalmology, Kanazawa University School of Medicine, Japan.

出版信息

Ophthalmic Res. 1995 Mar-Apr;27(2):110-7. doi: 10.1159/000267609.

DOI:10.1159/000267609
PMID:8538983
Abstract

Peak latencies of pattern electroretinogram (PERG) were compared between glaucomatous eyes and non-glaucomatous eyes. Contrast threshold for motion perception (CTMP) was also measured with a new device in addition to routine static contrast sensitivity, static visual field and visual acuity. In the present recording, configurations for PERG, i.e. low reversal rate, low mean luminance and presence of background illumination, the PERG peak and trough (P1 and N2, respectively) latencies, were significantly prolonged in the glaucomatous eyes. Although both of the two PERG latencies were strongly correlated with the CTMP, only the P1 peak latency was strongly correlated with the perimetric indices. These results suggest that the P1 and N2 latencies reflect different aspects of signal processing in the retina, especially for moving targets.

摘要

比较了青光眼患者与非青光眼患者的图形视网膜电图(PERG)的峰值潜伏期。除了常规的静态对比敏感度、静态视野和视力外,还使用一种新设备测量了运动感知对比阈值(CTMP)。在本次记录中,PERG的参数设置,即低反转率、低平均亮度和背景照明的存在,青光眼患者眼睛的PERG峰和谷(分别为P1和N2)潜伏期显著延长。虽然两个PERG潜伏期均与CTMP密切相关,但只有P1峰潜伏期与视野指标密切相关。这些结果表明,P1和N2潜伏期反映了视网膜信号处理的不同方面,特别是对于移动目标。

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