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精神分裂症中逆向掩蔽缺陷与平稳跟踪功能障碍之间的关系?

Relation between backward masking deficits and smooth pursuit dysfunction in schizophrenia?

作者信息

Allen J S

机构信息

Department of Anthropology, University of Auckland, New Zealand.

出版信息

Optom Vis Sci. 1995 Jul;72(7):493-501.

PMID:8539013
Abstract

Backward masking deficit and smooth pursuit dysfunction are cognitive, information processing markers associated with schizophrenia. In schizophrenia, backward masking is typically manifest as a longer interstimulus interval over which a mask is still effective in interfering with the processing of a preceding target. Smooth pursuit dysfunction is characterized by saccadic smooth pursuit, saccadic intrusions, and low-gain pursuit. Although the natures of the two markers relative to schizophrenia are somewhat different (e.g., smooth pursuit dysfunction is a genetic marker; backward masking is associated more strongly with negative symptoms, poor prognosis schizophrenia), information processing theory indicates a possible neurocognitive relation between the two.

摘要

逆向掩蔽缺陷和平滑跟踪功能障碍是与精神分裂症相关的认知、信息处理指标。在精神分裂症中,逆向掩蔽通常表现为掩蔽仍能有效干扰先前目标处理的更长刺激间隔。平滑跟踪功能障碍的特征是扫视性平滑跟踪、扫视性侵入和低增益跟踪。尽管这两个指标与精神分裂症的性质有所不同(例如,平滑跟踪功能障碍是一种遗传指标;逆向掩蔽与阴性症状、预后不良的精神分裂症关联更强),但信息处理理论表明两者之间可能存在神经认知关系。

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