Varon J, Fromm R E
Department of Anesthesiology and Critical Care, University of Texas MD Anderson Cancer Center, Houston, USA.
Postgrad Med. 1996 Jan;99(1):189-91, 195-6, 199-200, passim.
Although hypertensive crises are now relatively uncommon, they often are life-threatening when they do occur and demand early recognition and management to minimize morbidity and mortality. Most patients have essential hypertension, and withdrawal from an antihypertensive drug is the most common cause of acute elevation of blood pressure. Short-acting parenteral agents are generally recommended for management of hypertensive crises. In most patients with hypertensive emergencies, the mean arterial pressure is lowered 25% over 2 to 4 hours. Both cerebral and coronary hypoperfusion must be avoided.
尽管高血压危象现在相对不常见,但一旦发生往往危及生命,需要早期识别和处理以尽量降低发病率和死亡率。大多数患者患有原发性高血压,停用抗高血压药物是血压急性升高的最常见原因。一般推荐使用短效胃肠外给药制剂来处理高血压危象。在大多数高血压急症患者中,平均动脉压在2至4小时内降低25%。必须避免脑和冠状动脉灌注不足。