Rona R J, Chinn S, Burney P G
Department of Public Health Medicine, UMDS, St Thomas' Hospital, London, UK.
Thorax. 1995 Sep;50(9):992-3. doi: 10.1136/thx.50.9.992.
Some doubts exist as to whether the increase in the prevalence of asthma is real or an artefact. The 10 year trend of asthma up to 1993 in England and Scotland was therefore assessed.
Information on asthma and bronchitis attacks, occasional wheeze, and persistent wheeze in the last 12 months, was obtained using a self administered questionnaire completed by the parents. Exactly the same questions were asked in 14 study areas in Scotland and 22 study areas in England in 1982 or 1983 and in 1992 or 1993 in 5-11 year old children.
The numbers of children with data for all respiratory illness were 5556 (85.2%) and 5801 (87.1%) in England and 3748 (90.4%) and 3738 (90.4%) in Scotland in 1982 and 1992, respectively. There was a significant increase in asthma attacks (approximately three times more in 1992 than in 1982) and occasional wheeze (30-60% more in 1992 than in 1982) in both sexes in England and Scotland. Persistent wheeze also increased in both countries, but the increase was significant only in England (30-40% more in 1992 than in 1982).
The study coincides with others that suggest that the increased prevalence of asthma may be due, in part, to changes in diagnostic behaviour. However, the continuing increase of persistent wheeze in the total sample suggests that part of the increase is real. There was no difference in the increase of persistent wheeze between Scotland and England, but the trend was only significant in England.
关于哮喘患病率的上升是真实存在还是人为造成的,存在一些疑问。因此,对英格兰和苏格兰截至1993年的哮喘10年趋势进行了评估。
通过家长自行填写的问卷,获取过去12个月内哮喘和支气管炎发作、偶尔喘息以及持续喘息的信息。1982年或1983年在苏格兰的14个研究区域以及英格兰的22个研究区域,对5至11岁儿童提出了完全相同的问题,并于1992年或1993年再次询问。
1982年和1992年,英格兰分别有5556名(85.2%)和5801名(87.1%)儿童提供了所有呼吸道疾病的数据,苏格兰分别有3748名(90.4%)和3738名(90.4%)儿童提供了数据。在英格兰和苏格兰,男女哮喘发作(1992年比1982年增加约三倍)和偶尔喘息(1992年比1982年增加30 - 60%)均显著增加。两国持续喘息也有所增加,但仅在英格兰增加显著(1992年比1982年增加30 - 40%)。
该研究与其他研究一致,表明哮喘患病率上升可能部分归因于诊断行为的变化。然而,总样本中持续喘息的持续增加表明部分增加是真实的。苏格兰和英格兰在持续喘息增加方面没有差异,但该趋势仅在英格兰显著。