Kayser F, Maes D, Wyns L, Lisgarten J, Palmer R, Lisgarten D, Willem R, Martins J C, Verheyden P, Biesemans M
High Resolution NMR Center, Free University of Brussels (VUB), Belgium.
Steroids. 1995 Oct;60(10):713-9. doi: 10.1016/0039-128x(95)00096-9.
The molecular structure of the steroids [1,2,5]oxadiazolo[3', 4':3,4]-5 alpha-pregn-16-en-20-one oxime, [1,2,5]oxadiazolo[3',4':3, 4':3,4]-5 alpha-pregn-16-en-20-one and [1,2,5]oxadiazole]3',4':3,4]-5 beta-pregn-16-en-20-one has been determined. The proton-proton distances in the solid state from previous crystallographic studies are compared with the corresponding distances from novel and previous solution NMR as well as from novel in vacuo modeling studies.
已确定甾体化合物[1,2,5]恶二唑并[3',4':3,4]-5α-孕甾-16-烯-20-酮肟、[1,2,5]恶二唑并[3',4':3,4']-5α-孕甾-16-烯-20-酮和[1,2,5]恶二唑并[3',4':3,4]-5β-孕甾-16-烯-20-酮的分子结构。将先前晶体学研究中固态下的质子-质子距离与来自新的和先前的溶液核磁共振以及新的真空模拟研究中的相应距离进行了比较。
