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某地区毒物控制中心二十年中毒物摄入情况的流行病学研究

Epidemiology of ingestions in a regional poison control center over twenty years.

作者信息

Wolfle J, Kowalewski S

机构信息

Poison Control Center Bonn, Department of Pediatrics, Rheinische Friedrich-Wilhelms-Universitat Bonn, Germany.

出版信息

Vet Hum Toxicol. 1995 Aug;37(4):367-8.

PMID:8540233
Abstract

This analysis was conducted to demonstrate the pattern and changes of potential intoxications reported to a German regional poison control center from 1974 to 1993. During this period 155,654 calls were reported of which 111,313 were analyzed. The remaining 44,341 were either of minor importance of preventive calls; 56% referred to children and 44% to adults. Substance categories most commonly implicated were drugs, with a yearly average of 37.6% of the total, followed by household articles (31.2%), plants (9.7%) and chemicals (5.9%). In pediatric cases household articles were the most frequent source of ingestion followed by drugs, plants and nutritional substances, whereas in adults drugs were followed by household articles, chemicals and pesticides. Only 13.4% of all ingestions were classified as toxic or very toxic. There were no major changes in the incidences of the different substance categories during the 20 years. However, there were some changes in the pharmaceuticals, probably due to the introduction of new drugs or the withdrawal of the OTC-status of selected drugs.

摘要

本次分析旨在展示1974年至1993年期间向德国某地区毒物控制中心报告的潜在中毒情况的模式及变化。在此期间,共接到155,654个电话报告,其中111,313个被分析。其余44,341个要么重要性较低,要么是预防性电话;56%涉及儿童,44%涉及成人。最常涉及的物质类别是药物,年均占总数的37.6%,其次是家用物品(31.2%)、植物(9.7%)和化学品(5.9%)。在儿科病例中,家用物品是最常见的摄入源,其次是药物、植物和营养物质,而在成人中,药物之后是家用物品、化学品和农药。所有摄入病例中只有13.4%被归类为有毒或剧毒。在这20年中,不同物质类别的发生率没有重大变化。然而,药物方面有一些变化,可能是由于新药的引入或某些药物非处方药地位的取消。

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