Azarov A V, Kotov A V, Pevtsova E I, Tolpygo S M, Lesnikova S Iu
Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Jul-Aug;45(4):765-74.
A new approach to estimation and prediction of morphine and cocaine effects was proposed based on the analysis of animal behaviour directed to a satisfaction of one of the main biological needs, thirst. Both morphine and cocaine did not essentially effect the level of the basic biological (drinking) motivation by the index of the general volume of liquid consumption. Both drugs produced opposite effects on the duration of recognition/manipulation and drinking components of the structure of water-reinforced instrumental act. The proposed methodology is of diagnostic and prognostic value in respect of the complex behavioural effects of the drugs and presumably some other active factors.
基于对动物为满足主要生物需求之一（口渴）而产生的行为分析，提出了一种估计和预测吗啡与可卡因作用的新方法。通过液体消耗总量指标来看，吗啡和可卡因对基本生物（饮水）动机水平均无实质性影响。两种药物对水强化工具性动作结构中的识别/操作和饮水成分的持续时间产生相反影响。所提出的方法对于药物以及可能的其他一些活性因素的复杂行为效应具有诊断和预后价值。
