Bjorkman D J, Carr-Locke D L, Lichtenstein D R, Ferrari A P, Slivka A, Van Dam J, Brooks D C
Endoscopy Center, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Am J Gastroenterol. 1995 Dec;90(12):2128-33.
Bile leaks are a well documented complication of biliary surgery, occurring more frequently with laparoscopic procedures. Endoscopic therapy with a long biliary endoprosthesis traversing the site of the leak is effective. We have evaluated the hypothesis that equalizing biliary and duodenal pressures with a short transpapillary stent is an equally effective therapy for bile leaks.
Thirty one consecutive patients presenting over a 52-month period with postsurgical bile leaks were evaluated. Patients had been treated with long endoprostheses (stents or nasobiliary tubes), sphincterotomy, or short transpapillary stents. The success, complication rate, need for additional therapy, and hospitalization time of each therapeutic approach were determined.
Endoscopic therapy was successful in all 25 patients in whom a bile leak could be documented. The clinical success, need for radiological drainage, length of hospitalization, and incidence of pancreatitis were similar for all methods of treatment.
These results confirm that endoscopic therapy is highly successful in the treatment of postoperative bile leaks and suggest that the mechanism of healing is the equalization of bile duct and duodenal pressures, allowing flow of bile into the duodenum. The endoscopic placement of short transpapillary stents without sphincterotomy is a temporary, effective, and technically simple method of pressure equalization. This should be considered as the primary therapy for most postoperative bile leaks.
胆漏是胆道手术中一种有充分文献记载的并发症,在腹腔镜手术中更常见。采用穿过漏口的长胆道内支架进行内镜治疗是有效的。我们评估了一种假说,即使用短的经乳头支架平衡胆道和十二指肠压力对胆漏同样是一种有效的治疗方法。
对连续31例在52个月期间出现术后胆漏的患者进行评估。患者接受过长内支架(支架或鼻胆管)、括约肌切开术或短经乳头支架治疗。确定每种治疗方法的成功率、并发症发生率、额外治疗需求及住院时间。
在所有25例可记录到胆漏的患者中,内镜治疗均成功。所有治疗方法的临床成功率、放射引流需求、住院时间及胰腺炎发生率相似。
这些结果证实内镜治疗在术后胆漏治疗中非常成功,并提示愈合机制是胆管和十二指肠压力平衡,使胆汁流入十二指肠。不进行括约肌切开术而内镜置入短经乳头支架是一种临时、有效且技术上简单的压力平衡方法。这应被视为大多数术后胆漏的主要治疗方法。