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使用鼻胆管引流和括约肌切开术成功治疗胆囊切除术后胆漏

Successful treatment of post-cholecystectomy bile leaks using nasobiliary tube drainage and sphincterotomy.

作者信息

Chow S, Bosco J J, Heiss F W, Shea J A, Qaseem T, Howell D

机构信息

Division of Gastroenterology, Lahey Hitchcock Northshore, Peabody, Massachusetts, USA.

出版信息

Am J Gastroenterol. 1997 Oct;92(10):1839-43.

PMID:9382048
Abstract

OBJECTIVE

Bile leaks are known complications of cholecystectomy. The combination of sphincterotomy and nasobiliary tube (NBT) drainage is effective for the immediate decompression of bile ducts and provides access for follow-up cholangiography. Our objective was to study, retrospectively, 19 patients who had undergone treatment for bile leaks with this combination between October 1991 and December 1995.

METHODS

Nineteen patients (15 F, 4 M) ages 23-83 yr (mean 50 yr) presented with bile leaks secondary to open cholecystectomy (n = 1) and laparoscopic cholecystectomy (n = 18). All patients had sphincterotomy and NBT placement. Symptoms, findings at ERCP, and outcome were reviewed.

RESULTS

Patients presented from 0 to 150 days after cholecystectomy (median = 2) with pain (n = 17), fever (n = 8), bile leakage in a surgical drain (n = 4), elevated liver tests (n = 8), and nausea and vomiting (n = 4). Fourteen patients had diagnostic imaging before endoscopic management. ERCP findings included cystic stump leak (n = 12), including one with a colocutaneous biliary fistula, gallbladder fossa leak (n = 3), right hepatic branch leak (n = 1), or no leak (n = 3). Three patients had choledocholithiasis. NBT drainage was used for a mean of 3.9 days (range 1-12 days). Fourteen patients had radiographic evidence of leak closure. One patient ultimately required surgical correction for a chronic colocutaneous biliary fistula. There were no early or late endoscopic complications.

CONCLUSIONS

Endoscopic management with nasobiliary drainage and sphincterotomy is effective for acute uncomplicated bile leaks but may not be adequate for chronic fistulas. The advantages over endoprostheses include access for subsequent cholangiography, improved biliary decompression, and catheter removal without further endoscopy.

摘要

目的

胆漏是胆囊切除术后已知的并发症。括约肌切开术联合鼻胆管(NBT)引流对胆管立即减压有效,并为后续胆管造影提供了途径。我们的目的是回顾性研究1991年10月至1995年12月间接受这种联合治疗胆漏的19例患者。

方法

19例患者(15例女性,4例男性),年龄23 - 83岁(平均50岁),出现开腹胆囊切除术(1例)和腹腔镜胆囊切除术(18例)后继发的胆漏。所有患者均接受了括约肌切开术和NBT置入。对症状、内镜逆行胰胆管造影(ERCP)检查结果及结局进行了回顾。

结果

患者在胆囊切除术后0至150天(中位数 = 2天)出现症状,包括疼痛(17例)、发热(8例)手术引流管胆汁漏(4例)、肝功能检查异常(8例)以及恶心呕吐(4例)。14例患者在内镜治疗前进行了诊断性影像学检查。ERCP检查结果包括胆囊管残端漏(12例),其中1例合并结肠皮肤胆管瘘、胆囊窝漏(3例)、右肝分支漏(1例)或无漏(3例)。3例患者有胆总管结石。NBT引流平均使用3.9天(范围1 - 12天)。14例患者有影像学证据显示漏口闭合。1例患者最终因慢性结肠皮肤胆管瘘需要手术矫正。无早期或晚期内镜并发症。

结论

鼻胆管引流和括约肌切开术的内镜治疗对急性非复杂性胆漏有效,但对慢性瘘管可能不足。与内置假体相比,其优点包括便于后续胆管造影、改善胆管减压以及无需进一步内镜检查即可拔除导管。

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