Glotzer M
Cell Biology Program, EMBL, Heidelberg, Germany.
Curr Biol. 1995 Sep 1;5(9):970-2. doi: 10.1016/s0960-9822(95)00190-4.
The ubiquitination and destruction of cyclins provides the way out of mitosis. A multiprotein complex polyubiquitinates cyclin B and promotes the separation of sister chromatids.
细胞周期蛋白的泛素化和降解为有丝分裂的退出提供了途径。一种多蛋白复合物对细胞周期蛋白B进行多聚泛素化,并促进姐妹染色单体的分离。