Japaze H, Garcia-Bunuel R, Woodruff J D
Obstet Gynecol. 1977 Apr;49(4):404-11.
This survey reports the past 38 years of experience with 192 cases of carcinoma of the vulva seen and treated at the Johns Hopkins Hospital. The review stresses the increased incidence of in situ neoplasia and the importance of individualization of therapy. Also the changing concepts in terminology (eg, the leukoplakic vulvitis of the past is the dystrophy of the present) suggest that the precursory alterations of previous discussions must be reviewed in the light of such an altered nomenclature. Features of epidemiologic and histologic importance are discussed.
本调查报道了约翰·霍普金斯医院过去38年中所见并治疗的192例外阴癌病例的经验。该综述强调原位肿瘤发病率的增加以及个体化治疗的重要性。此外，术语概念的变化（例如，过去的白斑性外阴炎现在称为营养不良）表明，必须根据这种改变后的命名法重新审视先前讨论中的前驱性改变。文中还讨论了具有流行病学和组织学重要性的特征。
