Between December and April there was a decrease in the concentration of gamma-globulins in the blood serum of 2 to 3 day old calves. 2. Calves with more symptoms of enteritis or omphalitis had lower concentrations of gammaglobulin. 3. Calves with higher body temperatures had lower concentrations. 4. Calves from primiparous cows had lower concentrations than calves from pluriparous. 5. Calves from young dams had lower concentrations than calves from older dams. 6. Calves, which were born by caesarian section had lower concentrations than calves which were born spontaneously or with other assistance.