Dardillat J, Trillat G, Larvor P
Ann Rech Vet. 1978;9(2):375-84.
Samples of colostrum were taken from 180 suckling cows (beef cows) from the same herd, during the 3 hours immediately after calving over a period of 4 consecutive years. Total proteins in colostrum-whey were estimated by the biuret method, and concentrations of gamma-globulins determined by electrophoresis. The significance of the close relationship between calf mortality and gamma-globulin levels in the maternal colostrum was studied. An attempt was made to define levels suitable for the health of the calves. Twin birth, age at calving and food intake towards the end of the gestation period, whatever their effect on calf mortality rate, did not bring about any significant variation in the levels of colostral gamma-globulins. On the other hand, however, cows suffering from various infections had lower levels of colostral gamma-globulins, and produced a higher calf mortality rate. A high degree of repeatability in gamma-globulin levels was observed in colostrums produced by the same cow during successive calvings. A correlation between colostral gamma-globulin levels of a particular cow and those of her female offspring was also found. This result, which should be controlled on a larger number of animals, suggests the possibility of an approach of the problem of calf mortality, using a sanitary and genetic selection designed to reduce the number of cows producing colostrum with low levels of gamma-globulins.
在连续4年的时间里，于产犊后的3小时内，从同一牛群的180头哺乳母牛（肉用母牛）采集初乳样本。采用双缩脲法估算初乳乳清中的总蛋白，并通过电泳测定γ-球蛋白浓度。研究了犊牛死亡率与母体初乳中γ-球蛋白水平之间密切关系的意义。试图确定适合犊牛健康的水平。双胎分娩、产犊时的年龄以及妊娠期末期的采食量，无论它们对犊牛死亡率有何影响，均未导致初乳γ-球蛋白水平出现任何显著变化。然而，另一方面，患有各种感染的母牛初乳中γ-球蛋白水平较低，且犊牛死亡率较高。在同一头母牛连续产犊期间所产的初乳中，观察到γ-球蛋白水平具有高度的重复性。还发现了特定母牛的初乳γ-球蛋白水平与其雌性后代的初乳γ-球蛋白水平之间存在相关性。这一结果（应在更多动物上进行验证）表明，有可能通过卫生和基因选择来减少产生低水平γ-球蛋白初乳的母牛数量，从而解决犊牛死亡率问题。
