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甲状腺相关眼病眼眶减压术后的长期视力预后

Long-term visual outcome following orbital decompression for dysthyroid eye disease.

作者信息

Hutchison B M, Kyle P M

机构信息

Department of Ophthalmology, Southern General Hospital, Glasgow, UK.

出版信息

Eye (Lond). 1995;9 ( Pt 5):578-81. doi: 10.1038/eye.1995.143.

Abstract

The records of 33 patients who had undergone inferior and medial wall orbital decompressions for compressive optic neuropathy due to dysthyroid eye disease were reviewed. The indication for surgery in 32 patients was a reduction in Snellen visual acuity. The remaining patient had bilateral optic disc swelling but normal visual acuity. Twenty-nine patients (88%) were treated with systemic steroids pre-operatively, which resulted in an improvement in vision in all cases. In the immediate post-operative period visual acuity either improved or the steroid-induced visual improvement was maintained as the steroids were tailed off. Long-term visual outcome, however, varied. In 19 patients (58%) visual acuity was maintained with no requirement for additional treatment. In 12 patients (36%) there was a subsequent deterioration in vision which responded to additional treatment with either systemic steroids, orbital radiotherapy or further orbital surgery. In 2 patients (6%) vision continued to deteriorate despite further treatment. We conclude that although orbital decompression has resulted in the long-term preservation of visual acuity in 94% of our patients, there remains a small subgroup (6%) in whom visual function continues to deteriorate despite all forms of treatment.

摘要

回顾了33例因甲状腺相关眼病导致压迫性视神经病变而接受眶下壁和内侧壁减压手术的患者记录。32例患者的手术指征是Snellen视力下降。其余1例患者双侧视盘肿胀但视力正常。29例患者(88%)术前接受了全身类固醇治疗,所有病例视力均有改善。在术后即刻,视力有所提高,或者随着类固醇药物逐渐减量,由类固醇药物引起的视力改善得以维持。然而,长期视力结果各不相同。19例患者(58%)视力得以维持,无需额外治疗。12例患者(36%)随后视力恶化,经全身类固醇、眼眶放疗或进一步眼眶手术等额外治疗后有所改善。2例患者(6%)尽管接受了进一步治疗,视力仍持续恶化。我们得出结论,尽管眶减压术使94%的患者长期视力得以保留,但仍有一小部分患者(6%),尽管接受了各种治疗,视觉功能仍继续恶化。

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