Sukenik S, Mayo A, Neumann L, Flusser D, Kleiner-Baumgarten A, Buskila D
Dept. of Medicine, Soroka Medical Center, Beer Sheba.
Harefuah. 1995 Aug;129(3-4):100-3, 159, 158.
26 patients with osteoarthritis of the knees were randomly divided into 2 groups of 13 each with patients of similar ages, sex distribution and duration and severity of disease. All were treated with daily baths at 34-35 degrees C for 20 min. containing Dead Sea bath salts (Group I) or sodium chloride (Group II). The study was double-blind and of 2 weeks duration. Patients were evaluated by a rheumatologist before, at the end of treatment and 1 month later. Clinical parameters evaluated included index of severity of osteoarthritis, patient's assessment of disease severity, range of movement of knees, soft tissue swelling, effusion and crepitus. There was significant improvement in the index of severity of osteoarthritis at the end of the treatment in both groups (p < 0.01). 1 month later, in Group I the significance of the index was still p < 0.01, but p < 0.05 in Group II. Patient's assessment of improvement was significant only in Group I at the end of the treatment period (p < 0.01). There was no statistical improvement in either group in the other parameters assessed.
26名膝关节骨关节炎患者被随机分为两组,每组13人,两组患者的年龄、性别分布、病程和疾病严重程度相似。所有患者均接受每日34 - 35摄氏度的水浴20分钟,其中一组使用死海浴盐(第一组),另一组使用氯化钠(第二组)。该研究为双盲研究,为期2周。在治疗前、治疗结束时及1个月后,由一名风湿病专家对患者进行评估。评估的临床参数包括骨关节炎严重程度指数、患者对疾病严重程度的评估、膝关节活动范围、软组织肿胀、积液和摩擦音。两组在治疗结束时骨关节炎严重程度指数均有显著改善(p < 0.01)。1个月后,第一组该指数的显著性仍为p < 0.01,而第二组为p < 0.05。仅在治疗期结束时,第一组患者对改善情况的评估具有显著性(p < 0.01)。在评估的其他参数方面,两组均无统计学上的改善。