Shikare S, Bashir K, Menon P S, Bapat R D, Tilve G H
Dept of Nuclear Medicine, K E M Hospital, Parel, Bombay.
J Postgrad Med. 1995 Jan-Mar;41(1):12-3.
A sixty year old female referred for thyroid and liver scintigraphy had a clinical history of progressive swelling in the neck with hepatomegaly. A large cold area was detected in the right thyroid lobe using 99mTc pertechnetate and in the right lobe of liver using 99mTc phytate. Subsequent whole body scan with 99mTC DMSA(V) showed avid tracer uptake in right lobe of thyroid and liver. Aspiration cytology of thyroid and liver showed medullary carcinoma of thyroid with its metastasis in liver. Histopathology following thyroidectomy confirmed the diagnosis. Thus 99mTc pentavalent DMSA contributes specificity to diagnose medullary carcinoma of thyroid and metastatic lesions.
一名60岁女性因甲状腺和肝脏闪烁扫描前来就诊,有颈部进行性肿胀伴肝肿大的临床病史。使用高锝[99mTc]酸盐在右甲状腺叶发现一个大的冷区,使用植酸钠[99mTc]在肝脏右叶发现一个大的冷区。随后用99mTc二巯基丁二酸(V)进行全身扫描,显示甲状腺右叶和肝脏有放射性示踪剂摄取。甲状腺和肝脏的细针穿刺活检显示甲状腺髓样癌伴肝转移。甲状腺切除术后的组织病理学证实了诊断。因此,99mTc五价二巯基丁二酸有助于诊断甲状腺髓样癌及其转移灶。