Domzał T
Kliniki Neurologicznej Centralnego Szpitala Klinicznego Wojskowej Akademii Medycznej, Warszawie.
Neurol Neurochir Pol. 1995 Jul-Aug;29(4):481-8.
Fifty-five patients were treated with botulin injections into the muscles showing dystonia, contracture or tremor. Twenty two of them had torticollis, 21 had blepharospasm, 10 had hemifacial spasm, and 2 had tremor. In all, 112 injections were done with good result in 64%, slight effect in 27% and without effect in 9% of the cases. Similar results have been reported from other centers in the world. Adverse effects were not significant and disappeared after several days or weeks. They included ptosis, speech and deglutition disturbances, general weakness and neurotic reactions. These adverse effects developed in 12 cases. In cases of tremor the dose as well as the technique of injections must be individualized. The method is an important therapeutic advance and can be applied in outpatient clinics.
55例患者接受了肉毒杆菌素注射治疗，注射部位为出现肌张力障碍、挛缩或震颤的肌肉。其中22例患有斜颈，21例患有眼睑痉挛，10例患有半面痉挛，2例患有震颤。总共进行了112次注射，64%的病例效果良好，27%的病例效果轻微，9%的病例无效。世界上其他中心也报告了类似的结果。不良反应不明显，几天后或几周后消失。不良反应包括上睑下垂、言语和吞咽障碍、全身无力和神经反应。12例出现了这些不良反应。对于震颤病例，注射剂量和技术必须个体化。该方法是一项重要的治疗进展，可应用于门诊诊所。
