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[生物促性腺素对大鼠坐骨神经再生影响的研究]

[Study of the effect of biogonadyl on the regeneration of the rat's sciatic nerve].

作者信息

Zimnoch L, Lewko J, Drozdowski W, Kozielec Z, Kozłowski A

机构信息

Zakładu Anatomii Patologicznej, Kliniki Neurologii Akademii Medycznej, Białymstoku.

出版信息

Neurol Neurochir Pol. 1995 Jul-Aug;29(4):525-35.

PMID:8544931
Abstract

Using electroneurographic and morphological methods the effect of Biogonadyl on the regeneration of sectioned and the sutured sciatic nerves was evaluated. The analysis of conduction parameters in the sciatic nerves during the 6-week experiment, although the results obtained were not statistically significant, suggests a beneficial effect of Biogonadyl upon regeneration processes in the nerves. Morphological and morphometric studies have demonstrated that Biogonadyl statistically significantly accelerated axon growth in the distal part of sciatic nerves. It did not, however, influence the processes of their maturation.

摘要

采用神经电图和形态学方法评估了双性腺激素对切断和缝合的坐骨神经再生的影响。在为期6周的实验中对坐骨神经传导参数进行分析,尽管所得结果无统计学意义,但提示双性腺激素对神经再生过程有有益作用。形态学和形态计量学研究表明,双性腺激素在统计学上显著加速了坐骨神经远端的轴突生长。然而,它并未影响其成熟过程。

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