Battista J J, Santon L W, Bronskill M J
Phys Med Biol. 1977 Mar;22(2):229-44. doi: 10.1088/0031-9155/22/2/004.
The electron density (e cm-3) of a tissue sample can be determined by measuring the fluence of photons which it Compton scatters from a narrow incident beam of X- or gamma-radiation. This technique has been applied successfully to diagnostic denistometry (bone, lung), and less successfully to whole body tomography. In this work, the physics of Compton scatter tomography is examined with emphasis on transverse section scanning. The two major limitations of the scatter technique, attenuation of the single scatter photon fluence (of interest), and contamination of this fluence by multiply-scattered photons, are studied and corrective procedures are proposed. The methods described are applied to a simple test phantom; it is concluded that transverse images with an electron density precision of approximately 5% are possible.
组织样本的电子密度（电子数/立方厘米）可通过测量其对X射线或γ射线窄入射束的康普顿散射光子注量来确定。该技术已成功应用于诊断密度测定（骨骼、肺部），而在全身断层扫描中的应用则不太成功。在这项工作中，对康普顿散射断层扫描的物理原理进行了研究，重点是横断面扫描。研究了散射技术的两个主要局限性，即单次散射光子注量（感兴趣的）的衰减以及该注量被多次散射光子的污染，并提出了校正程序。所描述的方法应用于一个简单的测试体模；得出的结论是，有可能获得电子密度精度约为5%的横断面图像。
