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[子宫畸形。诊断、预后及治疗]

[Uterine malformations. Diagnosis, prognosis and treatment].

作者信息

Brun J L, Lemoine P

机构信息

Clinique Gynécologique, Hôpital Saint-André, Bordeaux.

出版信息

Presse Med. 1995 Nov 18;24(35):1658-62.

PMID:8545386
Abstract

Malformations of the uterus result from a variety of anomalies during embryogenesis from the 6th to the 17th week of development. Agenesia (not discussed here) should be distinguished from unicornis, pseudo-unicornis, bicornis, bipartitus and communicating uteri (Musset's classification). Such malformations occur in 3 to 4% of all women. Sonography provides the most useful information for diagnosis and should be used as first intention examination together with a work-up to determine extension. In certain cases, hysterography and laparoscopy may be required. Sterility is not increased in women with a malformation of the uterus, but fecundity is reduced due to a high rate of spontaneous abortions (30 to 40%) and premature births (15 to 45%). Obstetrical prognosis in case of a partitioned uterus can be improved by hysteroscopic resection of the partition. Most authors propose endoscopic treatment when a malformation of the uterus is diagnosed during a sterility work-up.

摘要

子宫畸形是由发育第6至17周胚胎形成过程中的各种异常所致。子宫发育不全(此处不作讨论)应与单角子宫、假单角子宫、双角子宫、双子宫及相通子宫(穆塞分类法)相鉴别。此类畸形在所有女性中发生率为3%至4%。超声检查为诊断提供了最有用的信息,应作为首选检查方法,并结合进一步检查以确定病变范围。在某些情况下,可能需要进行子宫输卵管造影和腹腔镜检查。子宫畸形女性的不孕率并未增加,但由于自然流产率较高(30%至40%)和早产率较高(15%至45%),生育能力会降低。对于纵隔子宫患者,通过宫腔镜切除纵隔可改善产科预后。大多数作者建议,在不孕症检查过程中诊断出子宫畸形时,应采用内镜治疗。

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