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胺碘酮复发性肺毒性。

Recurrent amiodarone pulmonary toxicity.

作者信息

Chendrasekhar A, Barke R A, Druck P

机构信息

University of Minnesota, Minneapolis, USA.

出版信息

South Med J. 1996 Jan;89(1):85-6. doi: 10.1097/00007611-199601000-00016.

Abstract

Amiodarone, a widely used antiarrhythmic drug, is associated with pulmonary toxicity, with an estimated mortality of 1% to 33%. Standard treatment for amiodarone pulmonary toxicity (APT) has been discontinuance of the drug and steroid therapy. We report a case of APT that recurred after withdrawal of steroids and failed to respond to reinstatement of steroid therapy. Recurrent APT is a rare clinical entity that has been reported only twice in recent literature.

摘要

胺碘酮是一种广泛使用的抗心律失常药物,与肺毒性相关,估计死亡率为1%至33%。胺碘酮肺毒性(APT)的标准治疗方法是停药和使用类固醇治疗。我们报告一例APT病例,该病例在停用类固醇后复发,且重新使用类固醇治疗无效。复发性APT是一种罕见的临床病症,最近的文献中仅报道过两例。

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