Sur R K, Levin V, Malas S, Donde B, Ahmed N, Retter E
Department of Radiation Oncology, University of the Witwatersrand, Johannesburg.
S Afr J Surg. 1995 Jun;33(2):67-9.
Ten patients with advanced metastatic squamous cell carcinoma of the middle third of the oesophagus were treated with palliative external radiotherapy and intraluminal brachytherapy. All patients had long lesions, 8-15 cm in length, and narrow lumens that did not allow the passage of a guidewire for dilatation. Improvement in dysphagia by more than 2 grades was seen in 9 of 10 patients. This finding was correlated with an increase in the size of the oesophageal lumen at the end of 6 weeks following treatment by barium swallow. No complications of treatment were noted in any patient. Low doses of external beam radiotherapy and high-dose-rate intraluminal brachytherapy can provide quick and effective palliation in advanced metastatic oesophageal carcinoma.
10例食管中段晚期转移性鳞状细胞癌患者接受了姑息性外照射放疗和腔内近距离放疗。所有患者均有较长病变，长度为8 - 15厘米，管腔狭窄，无法通过导丝进行扩张。10例患者中有9例吞咽困难改善超过2级。这一发现与治疗后6周钡餐检查时食管管腔大小增加相关。所有患者均未出现治疗并发症。低剂量外照射放疗和高剂量率腔内近距离放疗可为晚期转移性食管癌提供快速有效的姑息治疗。
