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[骨盆部治疗抵抗性残留肿瘤的动脉内治疗]

[Intra-arterial treatment of therapy-resistant residual tumors of the pelvis].

作者信息

Görich J, Hasan I, Kunze V, Sittek H, Brensing K A, Reiser M, Layer G, Rilinger N, Sokiranski R, Steudel A

机构信息

Universitätsklinik Bonn-Venusberg.

出版信息

Strahlenther Onkol. 1995 Dec;171(12):671-8.

PMID:8545787
Abstract

PURPOSE

Evaluation of intraarterial cancer treatment in recurrent pelvic tumors, which were resistent to other treatment modalities.

PATIENTS AND METHODS

Ninety-seven patients suffering from pelvic recurrences originating from bladder (n = 40), rectum (n = 19), cervix (n = 21) oder other organs (n = 17) were treated by intraarterial chemotherapy (111 times) or transcatheter embolisation (52 times).

RESULTS

Less than 20% of our patients had remission of the tumor burden but tumor symptoms (especially pain and bleeding) could be controlled in 35 to 87% of the patients. The main complication was a muscle necrosis after intraarterial chemotherapy because of recurrent bladder cancer.

CONCLUSION

Intraarterial cancertherapy is a useful procedure for symptomatic treatment of tumor symptoms especially in case of bleeding. Local tumor control can only be achived in a minority of the patients.

摘要

目的

评估动脉内癌症治疗对复发性盆腔肿瘤的疗效,这些肿瘤对其他治疗方式耐药。

患者与方法

97例盆腔复发患者,原发部位分别为膀胱(40例)、直肠(19例)、宫颈(21例)或其他器官(17例),接受了动脉内化疗(111次)或经导管栓塞治疗(52次)。

结果

不到20%的患者肿瘤负荷减轻,但35%至87%的患者肿瘤症状(尤其是疼痛和出血)得到控制。主要并发症是因复发性膀胱癌行动脉内化疗后出现肌肉坏死。

结论

动脉内癌症治疗对于肿瘤症状的对症治疗是一种有用的方法,尤其是在出血的情况下。只有少数患者能够实现局部肿瘤控制。

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Proton beam therapy for invasive bladder cancer: a prospective study of bladder-preserving therapy with combined radiotherapy and intra-arterial chemotherapy.质子束疗法治疗浸润性膀胱癌:一项联合放疗和动脉内化疗的保膀胱治疗前瞻性研究。
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[Treatment of lower urinary tract and pelvic malignancies by the transcatheter chemotherapy of the gluteus inferior artery and by embolization of the internal iliac artery].经臀下动脉导管化疗及髂内动脉栓塞治疗下尿路及盆腔恶性肿瘤
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