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佐剂对鸡新城疫口服疫苗接种的影响。

The influence of adjuvants on oral vaccination of chickens against Newcastle disease.

作者信息

Rehmani S F, Spradbrow P B

机构信息

Department of Veterinary Pathology, University of Queensland, Brisbane, Australia.

出版信息

Vet Microbiol. 1995 Sep;46(1-3):63-8. doi: 10.1016/0378-1135(95)00072-i.

Abstract

Living V4 strain Newcastle disease vaccine was given to chickens orally. The inclusion of DEAE-dextran, Quil-A or TiterMax in the vaccine, or delivering the vaccine as Iscoms, did not enhance the serological response. The immediate serological response to living V4 vaccine was enhanced in the presence of Avridine. Chickens produced a low serological response to oral administration of inactivated V4 vaccine. This response was not enhanced in the presence of Avridine.

摘要

将活V4株新城疫疫苗经口接种给鸡。在疫苗中添加二乙氨基乙基葡聚糖、Quil-A或TiterMax,或以免疫刺激复合物(Iscoms)形式递送疫苗,均未增强血清学反应。在有阿弗立定存在的情况下,对活V4疫苗的即时血清学反应增强。鸡对口服灭活V4疫苗产生的血清学反应较低。在有阿弗立定存在的情况下,这种反应未增强。

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