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降糖药物对脲酶的抑制作用(作者译)

[Inhibition of urease by hypoglycaemic drugs (author's transl)].

作者信息

Herrera J, Sabater J, Molina J

出版信息

Rev Esp Fisiol. 1977 Mar;33(1):37-9.

PMID:854647
Abstract

The effect of oral hypoglycaemic drugs (derived from sulphonylurea) on urease activity in the quantitative determination of urea has been studied. These compounds have been found to produce a competitive inhibition of enzyme activity with respect to substrate. Possible interference of these antidiabetic agents upon urea analysis is discussed.

摘要

研究了口服降糖药(磺脲类衍生物)在尿素定量测定中对脲酶活性的影响。已发现这些化合物对底物的酶活性产生竞争性抑制作用。讨论了这些抗糖尿病药物对尿素分析可能产生的干扰。

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