Herrera J, Sabater J, Molina J
Rev Esp Fisiol. 1977 Mar;33(1):37-9.
The effect of oral hypoglycaemic drugs (derived from sulphonylurea) on urease activity in the quantitative determination of urea has been studied. These compounds have been found to produce a competitive inhibition of enzyme activity with respect to substrate. Possible interference of these antidiabetic agents upon urea analysis is discussed.
研究了口服降糖药（磺脲类衍生物）在尿素定量测定中对脲酶活性的影响。已发现这些化合物对底物的酶活性产生竞争性抑制作用。讨论了这些抗糖尿病药物对尿素分析可能产生的干扰。
