韦格纳肉芽肿病的流行病学。基于人群数据源对五年期间患病率、年死亡率及疾病地理分布的估计。
The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources.
作者信息
Cotch M F, Hoffman G S, Yerg D E, Kaufman G I, Targonski P, Kaslow R A
机构信息
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
出版信息
Arthritis Rheum. 1996 Jan;39(1):87-92. doi: 10.1002/art.1780390112.
OBJECTIVE
To estimate the prevalence, annual mortality, and geographic distribution of Wegener's granulomatosis.
METHODS
Analysis of national vital statistics data and hospitalization data from a national survey and from all New York State inpatient facilities.
RESULTS
Between 1979 and 1988, 1,784 death certificates in the United States listed Wegener's granulomatosis as a cause of death. Nationally, an estimated 10,771 hospitalizations included Wegener's granulomatosis among the discharge diagnoses. In New York State, there were 978 hospitalizations among 571 individuals with Wegener's granulomatosis.
CONCLUSION
The prevalence of Wegener's granulomatosis in the United States is approximately 3.0 per 100,000 persons. Clear differences in the geographic distribution of Wegener's granulomatosis are apparent when analysis consider rates of disease in individual counties. Contrary to previous reports, associations between disease exacerbations and season were not apparent.
目的
评估韦格纳肉芽肿的患病率、年死亡率及地理分布情况。
方法
分析国家生命统计数据以及来自一项全国性调查和纽约州所有住院机构的住院数据。
结果
1979年至1988年间，美国有1784份死亡证明将韦格纳肉芽肿列为死因。在全国范围内，估计有10771例住院病例在出院诊断中包含韦格纳肉芽肿。在纽约州，571例韦格纳肉芽肿患者中有978次住院治疗。
结论
美国韦格纳肉芽肿的患病率约为每10万人中3.0例。当分析各县的疾病发生率时，韦格纳肉芽肿的地理分布存在明显差异。与之前的报告相反，疾病加重与季节之间没有明显关联。
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