McCombe A W, Kwok V, Hawke W M
Department of Otolaryngology University of Toronto, Canada.
Clin Otolaryngol Allied Sci. 1995 Aug;20(4):348-51. doi: 10.1111/j.1365-2273.1995.tb00057.x.
Third-octave sound analysis was performed on the snoring sounds of nine subjects with obstructive sleep apnoea (OSA) and 18 with simple snoring. Both groups demonstrated a large low frequency peak in linear sound levels at around 80 Hz. However, the OSA group displayed a substantially larger high frequency sound component. We utilized this fact in the development of an acoustic index (Hawke Index: HI) which describes the ratio between the overall A-weighted and linear sound levels for the recorded snoring sound of each subject [HI = dB(A)/dB(SPL) for Lmax]. There was a significant positive correlation between the apnoea/hypopnoea index and the HI (r = 0.73, t = 5.3, 25df, P < 0.001). If a value of 0.90 or greater was taken as diagnostic of OSA, the HI exhibited 67% sensitivity, 100% specificity, 100% positive and 86% negative predictive accuracy. With further development, we believe this acoustic phenomena may have a role as a screening test in the diagnosis of OSA.
对9名阻塞性睡眠呼吸暂停（OSA）患者和18名单纯打鼾者的鼾声进行了倍频程声音分析。两组在80Hz左右的线性声级上均表现出一个较大的低频峰值。然而，OSA组显示出一个明显更大的高频声音成分。我们利用这一事实开发了一种声学指数（霍克指数：HI），该指数描述了每个受试者记录的鼾声的总体A加权声级与线性声级之间的比率[Lmax时HI = dB(A)/dB(SPL)]。呼吸暂停/低通气指数与HI之间存在显著正相关（r = 0.73，t = 5.3，25df，P < 0.001）。如果将0.90或更高的值作为OSA的诊断标准，HI的敏感性为67%，特异性为100%，阳性预测准确性为100%，阴性预测准确性为86%。随着进一步发展，我们相信这种声学现象可能在OSA的诊断中作为一种筛查测试发挥作用。
