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水貂醋酸苯汞中毒

Phenylmercuric acetate intoxication in mink.

作者信息

Borst G H, Van Lieshout C G

出版信息

Tijdschr Diergeneeskd. 1977 Apr 15;102(8):495-503.

PMID:854915
Abstract

Mink died following an incidental phenylmercuric acetate (PMA) intoxication. Mortality was restricted to the older animals (31% in the females and 40% in the males). Of all organs the kidneys were most seriously damaged (tubulonephrosis) and contained the highest residual levels of mercury. No lesions were observed in the central nervous system. Twenty-one weeks after exposure mercury residues had declined to normal levels. The half-time of disappearance of mercury was 10 days in skeletal muscle, 22 days in kidneys, 27 days in brain and 36 days in liver. The reproductivity of the surviving mink was not affected by the PMA-intoxication.

摘要

水貂因意外摄入醋酸苯汞(PMA)而死亡。死亡率仅限于年龄较大的动物(雌性为31%,雄性为40%)。在所有器官中,肾脏受损最为严重(肾小管肾炎),汞残留水平最高。中枢神经系统未观察到病变。接触后21周,汞残留量已降至正常水平。汞在骨骼肌中的消失半衰期为10天,在肾脏中为22天,在大脑中为27天,在肝脏中为36天。存活水貂的繁殖能力未受PMA中毒影响。

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