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气动压迫袜在预防心脏手术后肺栓塞方面的疗效。

The efficacy of pneumatic compression stockings in the prevention of pulmonary embolism after cardiac surgery.

作者信息

Ramos R, Salem B I, De Pawlikowski M P, Coordes C, Eisenberg S, Leidenfrost R

机构信息

Department of Cardiology, St. Luke's Hospital, Chesterfield, Md, USA.

出版信息

Chest. 1996 Jan;109(1):82-5. doi: 10.1378/chest.109.1.82.

Abstract

INTRODUCTION

Pneumatic compression stocking (PCS) devices have been introduced to decrease the incidence of postoperative deep venous thrombosis (DVT). However, their role in the prophylaxis against pulmonary embolism (PE) remains unclear. This study was undertaken to compare the prophylactic effectiveness of subcutaneous heparin (SCH) alone vs the combined use of PCS and SCH in the prevention of PE following cardiac surgery.

METHODS

We studied 2,551 consecutive patients who underwent cardiac surgery over a 10-year period. They were randomly allocated to two groups. Group A included 1,196 patients who were treated with 5,000 U of SCH every 12 h and group B included 1,355 patients treated with a combined prophylactic regimen of PCS and SCH.

RESULTS

The diagnosis of PE was established in 69 patients by either high-probability ventilation perfusion scan, pulmonary angiogram, or autopsy. The incidence of PE in group A patients was 4% (48/1,196) and in group B was 1.5% (21/1,355). The concomitant use of bilateral PCS and SCH reduced the frequency of postoperative PE in 62% in comparison to the prophylaxis with SCH alone (p < 0.001).

CONCLUSIONS

These data suggest that the combined prophylactic method of bilateral PCS and SCH is superior to SCH alone in the prevention of PE after cardiac surgery.

摘要

引言

气压式压缩袜(PCS)装置已被用于降低术后深静脉血栓形成(DVT)的发生率。然而,其在预防肺栓塞(PE)方面的作用仍不明确。本研究旨在比较皮下注射肝素(SCH)单独使用与联合使用PCS和SCH在心脏手术后预防PE的效果。

方法

我们研究了在10年期间连续接受心脏手术的2551例患者。他们被随机分为两组。A组包括1196例患者,每12小时接受5000 U的SCH治疗,B组包括1355例接受PCS和SCH联合预防方案治疗的患者。

结果

通过高概率通气灌注扫描、肺血管造影或尸检确诊69例PE患者。A组患者的PE发生率为4%(48/1196),B组为1.5%(21/1355)。与单独使用SCH预防相比,双侧PCS和SCH联合使用使术后PE的发生率降低了62%(p<0.001)。

结论

这些数据表明,双侧PCS和SCH联合预防方法在预防心脏手术后PE方面优于单独使用SCH。

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