van der Maten G D
Department of Obstetrics and Gynaecology, Bosch Medicentrum, 's-Hertogenbosch, The Netherlands.
Eur J Obstet Gynecol Reprod Biol. 1995 Jul;61(1):63-4. doi: 10.1016/0028-2243(95)02154-k.
In the present study, besides the effect on blood pressure, the effects of a low sodium diet in pregnancy on maternal energy and nutrient intake, calcium metabolism, zinc and magnesium status, weight gain and body fat storage were investigated. No effect of the low sodium diet in pregnancy on the course of blood pressure and the incidence of hypertensive disorders was observed. The reduction in sodium intake also caused a significant reduction in the intake of energy, protein, carbohydrates, fat, calcium, zinc, magnesium, iron and cholesterol. The reduced intake of calcium, zinc and magnesium in the women on the low sodium diet did not result in significant changes in circulating total calcium, ionized calcium, parathyroid hormone, zinc, alkaline phosphatase or magnesium, probably because of homeostatic adaptations by the kidneys. In the women on the low sodium diet non-significant reductions in weight gain (1.5 kg) and fat mass gain (0.9 kg) over pregnancy were observed. These reductions in weight and fat mass gain were more pronounced (3.4 kg (P = 0.003) and 1.3 kg (P = 0.15), respectively) when only the data of the women with good compliance were analyzed. The use of a low sodium diet in pregnancy did not have significant effects on infant birth weight, placental weight or other pregnancy outcome variables.
在本研究中,除了对血压的影响外,还研究了孕期低钠饮食对母体能量和营养摄入、钙代谢、锌和镁状态、体重增加及体脂储存的影响。未观察到孕期低钠饮食对血压进程和高血压疾病发病率有影响。钠摄入量的减少还导致能量、蛋白质、碳水化合物、脂肪、钙、锌、镁、铁和胆固醇的摄入量显著降低。低钠饮食女性钙、锌和镁摄入量的减少并未导致循环总钙、离子钙、甲状旁腺激素、锌、碱性磷酸酶或镁发生显著变化,这可能是由于肾脏的稳态适应作用。观察到低钠饮食女性孕期体重增加(1.5千克)和脂肪量增加(0.9千克)有不显著的减少。仅分析依从性良好女性的数据时,体重和脂肪量增加的减少更为明显(分别为3.4千克(P = 0.003)和1.3千克(P = 0.15))。孕期使用低钠饮食对婴儿出生体重、胎盘重量或其他妊娠结局变量没有显著影响。