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小鼠T细胞受体可变基因片段家族。

Mouse T-cell receptor variable gene segment families.

作者信息

Arden B, Clark S P, Kabelitz D, Mak T W

机构信息

Paul-Ehrlich-Institute, Langen, Germany.

出版信息

Immunogenetics. 1995;42(6):501-30. doi: 10.1007/BF00172177.

DOI:10.1007/BF00172177
PMID:8550093
Abstract

All mouse T-cell receptor alpha/delta, beta, and gamma variable (Tcra/d-, b-, and g-V) gene segments were aligned to compare the sequences with one another, to group them into subfamilies, and to derive a name which complies with the standard nomenclature. It was necessary to change the names of some V gene segments because they conflicted with those of other segments. The traditional classification into subfamilies was re-evaluated using a much larger pool of sequences. In the mouse, most V gene segments can be grouped into subfamilies of closely related genes with significantly less similarity between different subfamilies.

摘要

将所有小鼠T细胞受体α/δ、β和γ可变区(Tcra/d-、b-和g-V)基因片段进行比对,以便相互比较序列、将它们分组为亚家族,并得出符合标准命名法的名称。由于某些V基因片段的名称与其他片段的名称冲突,因此有必要对其进行更改。利用数量多得多的序列库对传统的亚家族分类进行了重新评估。在小鼠中,大多数V基因片段可被分组为密切相关基因的亚家族,不同亚家族之间的相似性明显较低。

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1
Mouse T-cell receptor variable gene segment families.小鼠T细胞受体可变基因片段家族。
Immunogenetics. 1995;42(6):501-30. doi: 10.1007/BF00172177.
2
Human T-cell receptor variable gene segment families.人类T细胞受体可变基因片段家族
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3
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Immunogenetics. 1995;42(6):531-40. doi: 10.1007/BF00172178.
4
Nomenclature for T-cell receptor (TCR) gene segments of the immune system. WHO-IUIS Nomenclature Sub-Committee on TCR Designation.免疫系统T细胞受体(TCR)基因片段的命名法。世界卫生组织-国际免疫学会联盟TCR命名法小组委员会。
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本文引用的文献

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Conservation of Tcrg-V5 and limited allelic sequence polymorphism of the other Tcrg-V genes used by mouse tissue-specific gd-T lymphocytes.小鼠组织特异性γδ-T淋巴细胞所使用的Tcrg-V5的保守性以及其他Tcrg-V基因的有限等位基因序列多态性。
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Comparison of human and mouse T-cell receptor variable gene segment subfamilies.人类和小鼠T细胞受体可变基因片段亚家族的比较。
Immunogenetics. 1995;42(6):531-40. doi: 10.1007/BF00172178.
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Human T-cell receptor variable gene segment families.人类T细胞受体可变基因片段家族
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